The Facility Description (NIH Application Format)

Facilities and Other Resources: University of Colorado Anschutz Medical Campus Genomics and Microarray Core Laboratory

Laboratory: The Genomics and Microarray Core Facility at the University of Colorado Anschutz Medical Campus has over 1580 square feet of lab space.

Clinical: Not applicable

Animal: Not applicable

Computers: in addition to over 20 Dell and HP desktop computers, the facility is equipped with the following server computers:

Illumina Hiseq NGS data processing server: 40TB hard drive array comprised of four (4x) Dell PowerEdge R610 Servers - each server node containing eight CPU quad cores at 2.27GHz and 48GB RAM

Illumina Hiseq NGS data storage arrays: two (2x) 100TB hard drive array - each array containing six CPU hex cores and 32GB RAM

Illumina Hiseq NGS data transfer (SFTP) server: 10TB hard drive array, four CPU quad cores at 3.2GHz, and 24GB RAM

Dell Precision T7500 Server for Ion Torrent PGM system: 12TB hard drive array, six CPU hex cores at 2.67GHz, and 48GB RAM

Office and Personnel: In addition to Dr. Bifeng Gao (Core Director) and Katrina Diener (Core Manager), the Genomics core has 7 full time PRAs, and two part time PRAs (webmaster 25%, IT 10%) working for the core. Dr. Gao has an office in close proximity to the core laboratory. His office is equipped with computers, printer, fax machine and a telephone.

Other: Five distinct bioinformatic packages for microarray and next generation sequencing data analysis. 1) Affymetrix GeneChip Software, 2) Illumina BeadStudio Data Analysis Software, Sequencing Control software and CASAVA, 3) GeneSpring by Agilent, 4) Ingenuity Pathway Analysis software by Ingenuity, 5) Genomics Suite by Partek.

Major equipment:
  • Illumina HiSeq 4000 Sequencing System
  • Illumina HiSeq 2000 Sequencing System
  • Illumina HiSeq 2500 Sequencing System
  • Illumina MiSeq Sequencing System
  • Illumina iScan and iScan accessory equipment
  • Life Technologies Ion PGM Sequencer
  • Affymetrix GeneChip Instrumentation System.
  • Affymetrix GeneTitan System
  • Agilent SureScan Microarray Scanner
  • Agilent Bravo
  • Somalogic SOMAscan Assay System
  • Fluidigm C1, BioMark HD, Juno, and Access Array
  • Bio-Rad CFX 96 real-time PCR system
  • Agilent 2100 Bioanalyzer
  • Agilent 2200 Tapestation
  • Nanodrop ND-1000 spectrophotometer
  • Nanodrop ND-3300 fluorospectrophotometer
  • Tecan infinite M200 pro
  • Covaris S220 High Performance Ultrasonicator